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. 2019 Apr 15;10:19. doi: 10.1186/s13293-019-0233-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Female Siah2KO adipocytes increase in size with HFD in white adipose tissue, but accumulate fewer crown-like structures and less fibrosis compared to male white adipose tissue. a H&E and b trichrome staining of HFD male (M) and female (F) wild-type and Siah2KO inguinal and perigonadal fat