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. 2019 Apr 15;10:19. doi: 10.1186/s13293-019-0233-y

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© The Author(s). 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Microarray analysis of brown fat transcriptomics in HFD-fed male and female mice. a–d Analysis of gene expression in male and female BAT samples. a Overlap of differentially expressed genes (nominal P < 0.001, absolute fold-change > 1.5) in male and female samples. b–d Mean-average plots for gene targets of transcription factors Nfe2l2 and Ppargc1a (male BAT samples) and Srebf1 (female BAT samples), based on over-representation analysis in Ingenuity Pathway Analysis tool. Transcription factor target genes are shown as solid circles, whereas the remaining genes on the microarray are shown as open circles