Table 2. PXR Activity of Compounds 14a, 17a, and 19ba.
Data represent mean values SD of at least three independent experiments.
Units are μM for EC50 and % versus T0901317.
Efficacy values are here used as measure of AlphaScreen signal change.
Data represent mean values SD of at least three independent experiments.
Units are μM for EC50 and % versus T0901317.
Efficacy values are here used as measure of AlphaScreen signal change.