Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| entry | ASIC1aa | ASIC2aa | ASIC1a/2aa |
|---|---|---|---|
| 1 (DA) | 56.9 ± 8.9 | 169.0 ± 18.1 | 45.2 ± 8.8 |
| 2a | >30 | 18.9 ± 6.9 | 10.9 ± 1.6 |
| 2b | >30 | >30 | >30 |
| 2c | >30 | 8.8 ± 2.0 | >30 |
| 2d | >30 | 16.3 ± 4.6 | >30 |
| 2e | >30b | >30 | >30 |
| 2f | >30 | >30 | >30 |
| 2g | >30 | 4.3 ± 0.5 | >30 |
| 2h | >30 | >30 | >30 |
| 2i | >30 | >30 | >30 |
IC50 were determined as described in the Supporting Information; they are expressed in μM and are the average value of at least n = 3 independent experiments ± SEM.
