Scheme 1. Synthetic Pathways of Compounds 2a–g and 3a–f.
Reagents and conditions: (a) NaNO2, 6 N HCl, H2O, 0–5 °C, 1 h; (b) phenol, 4 N NaOH, 0–5 °C, 1 h; (c) oxone, CH2Cl2, H2O, r.t., 4 h; (d) 2-(4-aminophenyl)ethanol, CH3COOH, r.t., 24–48 h.
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