Figure 5.

Ion currents in UCB-iNs and BM-iNs: (a) the voltage-clamp protocol used in all experiments (200 ms step pulses from -120 to +50 mV in 10 mV increments from a holding voltage of -70 mV); (b) iN-UCBs or iN-BMs with complex neuron-like morphology were selected for electrophysiological recordings; (c) representative traces of the currents recorded from the control or induced cells. UCB cells presented potassium-like currents, but Na⁺-like currents were not detected. (d) Current-to-voltage relationships. The data are presented as the mean ± SEM.