Table 3.

Effects of extracellular cardiolipin on different cell types.

Target cell	Effect
Murine RAW 264.7 macrophages	Upregulated phagocytic activity [92]
Primary murine microglia	Upregulated phagocytic activity [109]
Human THP-1 monocytic cells	Attenuated IFN-γ-induced secretion of TNF-α [109]
Murine BV-2 microglial cells	Attenuated LPS-induced release of NO [109]
Human promyelocytic HL-60 cells	Attenuated LPS-primed NADPH oxidase-dependent respiratory burst leading to decreased ROS release [109]