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Human MSC formed mesenspheres after coculture with REH cells. MSC and LN-MSC spheres formed (a) without or (b) with induction. MSC or LN-MSC were previously labelled with CFSE. Representative photographs of mesenspheres are shown at different magnifications (10x, 20x, and 40x). (c) Mean number of spheres with a diameter > 100 μm in the different culture conditions. Results are expressed as mean ± SEM (p values: nonparametric one-way ANOVA; ∗∗ p < 0.01 and ∗∗∗ p < 0.001).
