Figure 7.

Participation of P2Y and P2X receptors in the cytosolic Ca²⁺ increase induced by ATP in olfactory neuronal precursors cells. To determine the specific relative contribution of either P2Y or P2X receptors to the enhancement of cytosolic Ca²⁺ induced by ATP, specific agonists were applied at the second stimulus and compared with the response to ATP. The response to UTP (P2Y agonist) reached 90% of the ATP response (a) (n = 5), whereas the P2X agonist α-β-methylene ATP only induced 10% of the ATP response (b) (n = 5 cells). Data represent the media ± SEM and were compared through a Student t test. ^∗p < 0.05.