Table 3.
Risk factors for ARDS development by univariate and multiple logistic regression analysis in SP patients.
| Parameters | Univariate/multivariate | P value | ||
|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | ||
| Age | 1.04 (0.83–1.36) | 0.61 | ||
| SOFA score | 0.85 (0.62–1.25) | 0.42 | ||
| LIS | 1.24 (0.91–1.78) | 0.17 | ||
| Body temperature | 1.12 (0.78–1.59) | 0.52 | ||
| Heart rate | 1.47 (1.03–2.13) | 0.021 | 0.99 (0.73–1.41) | 0.75 |
| SBP | 1.22 (0.85–1.79) | 0.25 | ||
| SpO2 | 1.03 (0.81–1.38) | 0.77 | ||
| BUN | 1.17 (0.73–1.65) | 0.61 | ||
| Creatinine | 1.04 (0.73–1.45) | 0.082 | 1.17 (0.72–1.88) | 0.65 |
| Lactate | 0.73 (0.53–0.99) | 0.018 | 1.03 (0.66–1.57) | 0.51 |
| Endocan | 1.65 (1.18–2.42) | 0.012 | 1.57 (1.14–2.25) | 0.021 |
| CRP | 1.21 (0.98–1.57) | 0.067 | 1.22 (0.95–1.68) | 0.17 |
| PaO2/FiO2 | 1.86 (1.17–3.12) | 0.024 | 1.57 (0.79–2.81) | 0.14 |
SP, severe pneumonia; ARDS, acute respiratory distress syndrome; SOFA, sequential organ failure assessment; LIS, lung injury score; SBP, systolic blood pressure; SpO2, oxygen saturation of pulse oximetry; BUN, blood urea nitrogen; CRP, C-reactive protein; PaO2/FiO2, ratio of partial pressure of arterial oxygen to fraction of inspired oxygen; CI, confidence interval; OR, odds ratio. ∗P < 0.05.