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Comparison of motor cortex tNAA/mIns and ALSFRS-R at Visit 1 between study withdrawers and completers. Patient subgroups were divided according to study withdrawal and completion. All 3 measures were significantly different between patients who withdrew due to ALS progression and patients who completed all visits (p < 0.05; unpaired, two-tailed t-tests). However, the most significant difference between groups was observed in the tNAA/mIns comparison (p < 0.001).
