Table 3.

Descriptive statistics of the included lipoprotein measures

Lipoprotein Concentration	CATHGEN		Healthy reference population^a
	Mean ± SD	Range (5^th-95^th percentile)	Mean ± SD	Range (5^th-95^th percentile)
LDL Particle (LDL-P) (nmol/L)
Total LDL-P	1452 ± 445	836 – 2277	1454 ± 393	891 – 2150
Large LDL-P	165 ± 159	0.07 – 464	309 ± 223	17 – 748
Medium LDL-P	132 ± 209	0.02 – 554	676 ± 405	0 – 1377
Small LDL-P	1156 ± 449	510 – 1973	469 ± 431	13 – 1318
HDL Particle (HDL-P) (μmol/L)
Total HDL-P	18.4 ± 3.9	12.3 – 24.9	24.0 ± 3.0	19.2 – 29.3
Large HDL -P	1.6 ± 1.3	0.4 – 4.3	2.5 ± 1.9	0.2 – 6.3
Medium HDL -P	4.3 ± 2.6	1.0 – 9.2	7.7 ± 2.7	3.7 – 12.6
Small HDL -P	12.4 ± 4.0	5.7 – 18.8	13.8 ± 3.4	8.1 – 19.6
TG-rich Lipoprotein Particle (TRL-P) (nmol/L)
Total TRL-P	133 ± 73.8	30.0 – 268	125 ± 61.6	42 – 239
Large TRL-P	2.7 ± 5.1	0.0 – 13.0	2.9 ± 6.5	0.0 – 12.8
Medium TRL-P	19.4 ± 20.6	0.0 – 59.7	17.9 ± 16.2	0.3 – 48.4
Small TRL-P	38.6 ± 32.5	0.07 – 98.8	56.5 ± 37.5	7.3 – 124
NMR-derived Lipid and Apolipoprotein (mg/dL)
LDL-C	97.8 ± 31.6	54.1 – 155	111± 30.7	63 – 163
HDL-C	44.3 ± 11.8	29.0 – 66.2	61.1 ± 14.4	41 – 88
Total triglycerides	106 ± 83.6	30.2 – 249	119 ± 89.8	53 – 127
Total cholesterol	166 ± 39.7	110 – 237	194 ± 36.5	116 – 209
Apolipoprotein B	81.0 ± 24.6	47.2 – 126	87.1 ± 23.6	53 – 127

All p-values for t-tests comparing the means between the two populations were <0.05, except for total LDL-P. HDL, high-density lipoprotein; LDL, low-density lipoprotein; NMR, nuclear magnetic resonance.

Comparison reference population includes healthy adult men (n=284) and women (n=414) between the ages of 18 and 84 (Matyus et al. 2014)