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ENM 083 has copper-dependent inhibitory activity against S. aureus. A, ENM 083 is a 2,2 pyridinyl thieno-pyrimidine. B, ENM 083 was assayed against S. aureus in a microtiter plate; metals were present at 50μM when indicated. Growth amounts were normalized to individual metal-only control wells. C, drops from the assay plate were spotted on agar to visualize bacteriostatic activity.
