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. 2018 Dec 28;219(9):1456–1463. doi: 10.1093/infdis/jiy692

Table 2.

Viral Load and CD4+ T-Cell Count Differences Between KIR Positives versus Negatives Under the Existence of Their Ligand HLA Alleles

R square B (95% CI) β P
Viral load, log copies/mL
HLA-C*02:02 + 0.07
KIR2DL1 + −1.7 (−3.7 to 0.3) −0.2 .1
KIR2DS1 + −0.6 (−1.3 to 0.08) −0.2 .08
HLA-C*16:01 + 0.2
KIR2DL2 + 0.7 (−1.2 to 2.6) 0.4 .5
KIR2DL3 + 1.6 (0.2 to 3.1) 0.5 .02
KIR2DS2 + −0.3 (−2.2 to 1.6) −0.1 .8
CD4+ T cell, counts/mm3
HLA-C*16:01 + 0.3
KIR2DL2 + −149 (−417 to 119) −0.5 .3
KIR2DL3 + −276 (−473 to −78) −0.5 .008
KIR2DS2 + 119 (−150 to 388) 0.4 .4

P values by multivariate linear regression model are shown.

Abbreviations: CI, confidence interval; HLA, human leukocyte antigen; KIR, killer immunoglobulin-like receptor.