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. 2018 Dec 28;219(9):1456–1463. doi: 10.1093/infdis/jiy692

Table 3.

CD4+ T-Cell Counts <200/mm3 or ART Initiation Rate Difference Among HLA-KIR Pairs

Variables aHR (95% CI) P
Sex, female 1.2 (0.7–1.9) .5
CD4+T cell, counts/mm3 0.9 (0.9–0.9) <.001
CD4/CD8 ratio 0.4 (0.1–1.0) .05
Viral load, log copies/mL 2.0 (1.5–2.6) <.001
HLA-C*06:02 + KIR2DL1 + 0.9 (0.5–1.7) .7
HLA-C*16:01 + KIR2DL3 + 1.9 (1.1–3.5) .02
HLA-B*44:03 + KIR3DL1 + 1.0 (0.4–2.6) .9
HLA-B*58:02 + KIR3DL1 + 1.5 (0.7–3.0) .3

Multivariate Cox hazard model analysis is shown.

Abbreviations: aHR, adjusted hazard ratio; ART, antiretroviral treatment; CI, confidence interval; HLA, human leukocyte antigen; KIR, killer immunoglobulin-like receptor.