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De novo peri-infarct expression of OXTR. (A, B) H&E staining identifies both white (A) and grey (B) matter infarcts in paraffin embedded frontal cortex tissue from VaD cases. Shown at 4× magnification. (C, D) OXTR IHC in adjacent sections revealed prominent expressions surrounding the white (C) and grey (D) matter microinfarcts. Shown at 4× (top) and 10× (bottom) magnification. The OXTR-immunoreactive profiles showed an astroglial typical morphology.
