FIGURE 9.
Gradient of OXTR expression in astrocytes and blood vessels relative to microinfarction site. (A) Photomicrograph shows dual-label IHC of OXTR and GFAP from Figure 8 with numbered insets as shown in (B). (B) OXTR expression is enriched in GFAP-immunopositive profiles in a field close to the microinfarction [3] and in the left part of fields [1] and [4] proximal to the lesion. In contrast, OXTR is minimal in GFAP-immunopositive profiles in a field farther from the microinfarction [2] and in the right part of fields [1] and [4] distal to the lesion. All fields shown at 20×. (C) OXTR-expressing astrocytes are indicated with black arrows, whereas vessels labeled with OXTR are indicated with black arrowheads and OXTR-negative astrocytes are labeled with asterisks. All fields shown at 40×. (D) Another field from the same section further demonstrates dual-labeled GFAP positive astrocytes and vessels expressing OXTR (40×).
