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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Adv Healthc Mater. 2018 Feb 14;7(10):e1701469. doi: 10.1002/adhm.201701469

Figure 5. In vitro BMDC activation by tough cryogels.

Figure 5.

(A) Fractions of CD86+ CD11c+ DCs after culture in tough and covalently crosslinked-only cryogels, as analyzed by flow cytometry. (B) Cumulative release of CpG-ODN from tough cryogels. (C) Fractions of CD86+ (left) and MHC II+ (right) CD11c+ DCs after culture in media alone, tough cryogels containing no CpG-ODN (Blank Tough), or tough cryogels delivering CpG-ODN after cryogels were previously allowed to release CpG-ODN for 3 days, 1 week or 2 weeks (3D Tough, 1W Tough and 2W Tough) prior to exposure to DCs. n = 4. Values presented were expressed as mean ± s.d. Data were analyzed by a two-tailed Student’s t-test or Welch’s t-test. * p < 0.05, ** p < 0.01, **** p < 0.0001.