Table 1.

Radiation dose estimates for a 70-kg adult male based on the biodistribution data for the huA33-TCO/¹⁷⁷Lu-DOTA-PEG₇-Tz PRIT system with a 24 h interval (left) and the directly-labeled ¹⁷⁷Lu-CHX-A˝-DTPA-huA33 radioimmunoconjugate (right).

	Pretargeting with huA33-TCO and ¹⁷⁷Lu-DOTA-PEG₇-Tz (24 h interval)	¹⁷⁷Lu-CHX-A˝-DTPA-huA33

Organ/Tissue	Absorbed Dose (mGy/MBq)	Absorbed Dose (mGy/MBq)
Adrenals	0.056	0.034
Brain	0.055	0.029
Breasts	0.053	0.028
Gallbladder Wall	0.06	0.035
LLI Wall	0.059	0.041
Small Intestine	0.066	0.082
Stomach Wall	0.057	0.048
ULI Wall	0.058	0.038
Heart Wall	0.065	0.076
Kidneys	0.055	0.168
Liver	0.039	0.156
Lungs	0.043	0.126
Muscle	0.036	0.129
Ovaries	0.057	0.034
Pancreas	0.056	0.035
Red Marrow	0.059	0.105
Osteogenic Cells	0.292	0.651
Skin	0.052	0.028
Spleen	0.035	0.131
Testes	0.054	0.030
Thymus	0.055	0.032
Thyroid	0.055	0.032
Urinary Bladder Wall	0.056	0.033
Uterus	0.057	0.034
Total Body	0.070	0.097

Effective Dose (mSv/MBq)	0.054	0.068