Table 3.
Representative biological functions for each module based on enrichment map clustering of gene ontology: biological process and Reactome terms
| Module | Expression in disease | No genes in module | Biological function |
| ME1 | UP | 1579 | Cilia organisation |
| ME2 | DOWN | 1404 | Blood vessel development |
| ME3 | UP | 396 | Extracellular Matrix organisation |
| ME4 | UP | 380 | Cell division/DNA replication/DNA repair |
| ME5 | UP | 371 | B-cell activation/unfolded protein response |
| ME6 | UP | 207 | Extracellular Matrix organisation |
| ME7 | DOWN | 204 | Leucocyte activation/degranulation |
| ME8 | DOWN | 188 | Cellular metabolic process |
| ME9 | DOWN | 163 | Response to bacteria/apoptosis/RNA transcription |
| ME10 | DOWN | 158 | Surfactant metabolism |
| ME11 | DOWN | 116 | T-cell activation/Major histocompatability complex (MHC) class I activity/interferon response |
| ME12 | DOWN | 107 | Leucocyte activation/degranulation |
| ME13 | DOWN | 80 | Muscle contraction/organ development |
| ME14 | UP | 75 | Contractile fibre/cell-extracellular matrix interactions |
| ME15 | DOWN | 58 | Cellular protein catabolic mechanism |
| ME16 | DOWN | 39 | Cell-cell junction organisation |