Skip to main content
. 2019 Apr 9;13:138. doi: 10.3389/fncel.2019.00138

Table 2.

Gene-environment correlation between CNR1 (rs7766029) and GABRA6 (rs3219151) polymorphisms and different types of recent negative life events.

CNR1 (rs7766029)
GABRA6 (rs3219151)
Stress type (within the last year) β S.E. STAT P β S.E. STAT P
Combined population sample of Budapest and Manchester
RLE – relationship -0.014 0.0114 -1.185 0.236 0.003 0.0113 0.244 0.808
RLE – financial 0.019 0.0156 1.191 0.234 -0.009 0.0155 -0.594 0.552
RLE – illness/personal -0.018 0.0185 -0.973 0.331 0.004 0.0183 0.232 0.817
RLE – social -0.025 0.0190 -1.332 0.183 0.010 0.0188 0.554 0.580
Budapest subsample
RLE – relationship -0.015 0.0185 -0.819 0.413 -0.012 0.0181 -0.661 0.509
RLE – financial 0.0002 0.0205 0.011 0.991 0.004 0.0201 0.200 0.842
RLE – illness/personal -0.040 0.0289 -1.373 0.170 0.062 0.0283 2.205 0.028
RLE – social 0.028 0.0300 0.922 0.357 0.033 0.0291 1.127 0.260
Manchester subsample
RLE – relationship -0.014 0.0144 -0.951 0.342 0.009 0.0145 0.596 0.551
RLE – financial 0.029 0.0221 1.313 0.189 -0.027 0.0222 -1.231 0.219
RLE – illness/personal -0.004 0.0241 -0.172 0.864 -0.039 0.0241 -1.616 0.106
RLE – social -0.060 0.0245 -2.459 0.014 -0.004 0.0246 -0.169 0.866

S.E., standard error of beta; STAT, coefficient t-statistic; RLE, number of recent negative life events (within the last year); RLE – financial, financial difficulties; RLE-illness/personal, recent illness and personal problems; RLE – relationship, intimate relationship problems; RLE – social, social network disturbances. We tested additive linear regression models. The effect allele is T in case of CNR1 rs7766029, and C in case of GABRA6 rs3219151. In the combined population sample of Budapest and Manchester there were no significant p-Values. Significant p-values (< 0.05) are marked in bold.