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. Author manuscript; available in PMC: 2019 Jun 5.
Published in final edited form as: Biochemistry. 2018 Mar 26;57(22):3146–3154. doi: 10.1021/acs.biochem.8b00142

Figure 1. The reactions and structure of GMPR.

Figure 1.

(A) The GMPR reaction. (B) GMPR active sites with NADPH in the IN and OUT conformations are displayed (PDB entry 2C6Q). Residues in contact with IMP are shown. This figure was produced with UCSF Chimera 17. (C) The partial reactions catalyzed by GMPR.