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. 2019 Apr 15;199(8):1020–1027. doi: 10.1164/rccm.201803-0428OC

Table 2.

Postnatal Hospitalization Data

  No Late Respiratory Disease (n = 86) [n (%) or Median (IQR)] Late Respiratory Disease (n = 135) [n (%) or Median (IQR)] P Value
Surfactant in delivery room 69 (80.2) 121 (89.6) 0.050
Mechanical ventilation support at 7 d 27 (31.4) 60 (44.4) 0.053
Echocardiogram findings at 7 d      
 PFO 74 (86.0) 105 (77.8) 0.127
 VSD 3 (3.5) 4 (3.0) 0.828
 Measurable TRJV 7 (8.1) 15 (11.1) 0.472
 RV hypertrophy 0 (0) 4 (3.0) 0.107
 RV dilation 0 (0) 6 (4.4) 0.047
 Septal wall flattening 20 (23.3) 55 (40.7) 0.007
 PDA 26 (30.2) 50 (37.0) 0.299
 PVD 23 (26.7) 67 (49.6) 0.001
PDA, medical treatment 36 (41.9) 50 (37.0) 0.052
PDA, surgical ligation 12 (14.0) 23 (17.0) 0.440
IVH (grade 3 or 4) 4 (4.7) 5 (3.7) 0.728
Necrotizing enterocolitis 10 (11.6) 25 (18.5) 0.171
Threshold retinopathy 5 (5.8) 24 (17.8) 0.010
BPD (NIH multilevel)     0.042
 None 20 (23.3) 20 (14.8)  
 Mild 34 (39.5) 45 (33.3)  
 Moderate 20 (23.3) 30 (22.2)  
 Severe 12 (14.0) 40 (29.6)  
BPD (dichotomous)     0.033
 No BPD 54 (62.8) 65 (48.1)  
 BPD 32 (37.2) 70 (51.9)  
PH at 36 wk PMA 5 (5.8) 23 (17.0) 0.014
Days on MV 6 (2–19) 20 (4–50) <0.001
Total oxygen days (NICU) 60 (40–96) 87 (47–112) 0.013
Length of NICU stay, d 83 (69–100) 97 (79–124) <0.001
Discharged on oxygen 45 (52.3) 76 (56.3) 0.563
Age successfully taken off oxygen, d 74 (46–138) 133 (59–265) 0.003

Definition of abbreviations: BPD = bronchopulmonary dysplasia; IQR = interquartile range; IVH = intraventricular hemorrhage; MV = mechanical ventilation; NICU = neonatal ICU; PDA = patent ductus arteriosus; PFO = patent foramen ovale; PH = pulmonary hypertension; PMA = postmenstrual age; PVD = pulmonary vascular disease; RV = right ventricle; TRJV = tricuspid regurgitant jet velocity; VSD = ventricular septal defect.