Table 2.
Postnatal Hospitalization Data
| No Late Respiratory Disease (n = 86) [n (%) or Median (IQR)] | Late Respiratory Disease (n = 135) [n (%) or Median (IQR)] | P Value | |
|---|---|---|---|
| Surfactant in delivery room | 69 (80.2) | 121 (89.6) | 0.050 | 
| Mechanical ventilation support at 7 d | 27 (31.4) | 60 (44.4) | 0.053 | 
| Echocardiogram findings at 7 d | |||
| PFO | 74 (86.0) | 105 (77.8) | 0.127 | 
| VSD | 3 (3.5) | 4 (3.0) | 0.828 | 
| Measurable TRJV | 7 (8.1) | 15 (11.1) | 0.472 | 
| RV hypertrophy | 0 (0) | 4 (3.0) | 0.107 | 
| RV dilation | 0 (0) | 6 (4.4) | 0.047 | 
| Septal wall flattening | 20 (23.3) | 55 (40.7) | 0.007 | 
| PDA | 26 (30.2) | 50 (37.0) | 0.299 | 
| PVD | 23 (26.7) | 67 (49.6) | 0.001 | 
| PDA, medical treatment | 36 (41.9) | 50 (37.0) | 0.052 | 
| PDA, surgical ligation | 12 (14.0) | 23 (17.0) | 0.440 | 
| IVH (grade 3 or 4) | 4 (4.7) | 5 (3.7) | 0.728 | 
| Necrotizing enterocolitis | 10 (11.6) | 25 (18.5) | 0.171 | 
| Threshold retinopathy | 5 (5.8) | 24 (17.8) | 0.010 | 
| BPD (NIH multilevel) | 0.042 | ||
| None | 20 (23.3) | 20 (14.8) | |
| Mild | 34 (39.5) | 45 (33.3) | |
| Moderate | 20 (23.3) | 30 (22.2) | |
| Severe | 12 (14.0) | 40 (29.6) | |
| BPD (dichotomous) | 0.033 | ||
| No BPD | 54 (62.8) | 65 (48.1) | |
| BPD | 32 (37.2) | 70 (51.9) | |
| PH at 36 wk PMA | 5 (5.8) | 23 (17.0) | 0.014 | 
| Days on MV | 6 (2–19) | 20 (4–50) | <0.001 | 
| Total oxygen days (NICU) | 60 (40–96) | 87 (47–112) | 0.013 | 
| Length of NICU stay, d | 83 (69–100) | 97 (79–124) | <0.001 | 
| Discharged on oxygen | 45 (52.3) | 76 (56.3) | 0.563 | 
| Age successfully taken off oxygen, d | 74 (46–138) | 133 (59–265) | 0.003 | 
Definition of abbreviations: BPD = bronchopulmonary dysplasia; IQR = interquartile range; IVH = intraventricular hemorrhage; MV = mechanical ventilation; NICU = neonatal ICU; PDA = patent ductus arteriosus; PFO = patent foramen ovale; PH = pulmonary hypertension; PMA = postmenstrual age; PVD = pulmonary vascular disease; RV = right ventricle; TRJV = tricuspid regurgitant jet velocity; VSD = ventricular septal defect.