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. 2017 May 3;7:25–35. doi: 10.2147/BLCTT.S87186

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© 2017 Chandesris et al. This work is published and licensed by Dove Medical Press Limited

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(A) Survival curves in midostaurin-untreated patients (French historical control group, n=44) according to WHO-defined systemic mastocytosis subtypes. (B) Survival curves in midostaurin-treated patients under cover of the French compassionate use program (n=28) according to WHO-defined systemic mastocytosis subtypes. Notes: (A) SM-AHNMD n=33; ASM n=5; MCL n=2; SSM n=2; MCS n=2. (B) SM-AHNMD n=18; ASM n=4; MCL n=3; SSM n=2; MCS n=1. The MCL and SSM curves have the same color because no death was registered, so curves are superimposed.

Abbreviations: AHNMD, associated clonal hematological non-mast cell lineage disease; ASM, aggressive systemic mastocytosis; MCL, mast cell leukemia; MCS, mast cell sarcoma; n, number; SM, systemic mastocytosis; SSM, smoldering systemic mastocytosis; WHO, World Health Organization.