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. 2017 Dec 11;7:85–93. doi: 10.2147/BLCTT.S132060

Table 3.

Outcomes of various induction regimens in blastic plasmacytoid dendritic cell neoplasm

Reference N Chemo regimen CR (%) Relapsea (%) Median overall survival (months)
Feuillard et al9 5 ALL 80 50 12
6 AML 100 100 14.5
10 Lymphoma 80 75 11
Dalle et al39 5 ALL 80 nr 16
10 AML 40 nr 19
20 Lymphoma 50 nr 11.5
Tsagarakis et al40 9 ALL 100 33.3 nr
6 AML 50 33.3 nr
4 Lymphoma 75 66.7 nr
Dietrich et al41 3 ALL 100 66.7 23
2 AML 50 100 19
1 Lymphoma 100 100 6
Lucioni et al29 9 ALL 78 29 12
4 Lymphoma 50 100 27.5
Hashikawa et al42 2 ALL 100 nr NR
4 AML 25 nr 5.5
11 Lymphoma 73 nr 11
Pagano et al14 15 ALL/lymphoma 67 60 12.3
26 AML 27 0 7.1
An et al43 3 ALL 67 0 15.1
1 AML 0 NA
2 Lymphoma 50 0
Kim et al44 4 Hyper-CVAD 50 100 17
2 ALL-like 100 100
Martín- Martín et al38 7 ALL 100 43 NR
9 AML 100 78 11
9 Lymphoma 78 100 10

Notes: Lymphoma (CHOP/CHOP-like).

a

% relapse out of those achieving a CR with induction. Some studies include patients who received HSCT in consolidation or in first relapse.

Abbreviations: nr, not reported; NR, not reached; CHOP, cyclophosphamide, doxorubicin, vincristine, prednisone; ALL, acute lymphoblastic leukemia; AML, acute myeloid leukemia; CVAD, cyclophosphamide, vincristine, doxorubicin, and dexamethasone; CR, complete remission; NA, not applicable; HSCT, hematopoietic stem cell transplantation.