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. 2019 Apr 16;17(4):e2006421. doi: 10.1371/journal.pbio.2006421

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Fig 1 — (A) Effect of intraperitoneal oxytocin on alcohol reinforcers earned by dependent and nondependent rats in 30-min alcohol self-administration sessions. (B) Effect of intraperitoneal oxytocin on breakpoint for alcohol on a PR schedule of reinforcement. (C) Effect of intranasal oxytocin on alcohol reinforcers earned by dependent and nondependent rats in 30-min alcohol self-administration sessions. (D) Effect of intranasal oxytocin on breakpoint for alcohol on a PR schedule of reinforcement. ^#Significant difference between dependent and nondependent rats (p < 0.05). *Significantly different from groups’ respective control condition (0 mg/kg; p < 0.05). EtOH, ethanol; FR1, fixed ratio 1; IN, intranasal; IP, intraperitoneal; PR, progressive ratio.