Table 2.
Bipolar Means (SD) |
Unipolar Means (SD) |
t | Sig. | |
---|---|---|---|---|
Medication Load | ||||
Mood stabilizers | 1.55 (1.21) | 0.50 (0.48) | 4.14 | <.001 |
Antidepressants | 1.14 (1.06) | 1.98 (1.66) | −2.2 | 0.03 |
Anxiolytics | 0.34 (0.32) | 0.24 (0.32) | 1.35 | 0.18 |
Baseline Clinical Characteristics | ||||
HAM-D-17 | 13.63 (7.61) | 16.82 (6.38) | 1.68 | 0.10 |
ACS | 4.35 (0.62) | 3.94 (0.69) | 2.31 | 0.03 |
BIS | 23.5 (6.14) | 16.82 (3.41) | 5.25 | <.000 |
BAS - Drive | 7.17 (3.03) | 4.33 (2.90) | 3.57 | 0.001 |
BAS-Reward | 11.75 (2.33) | 8.58 (3.75) | 3.66 | 0.001 |
BAS-Fun Seeking | 6.21 (3.35) | 4.93 (2.82) | 1.51 | 0.14 |
Note. Standardized medication load metric was calculated for each individual patient by dividing each of the patient’s prescribed medication dosages by the World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology Anatomical Therapeutic Chemical Defined Daily Dose for that medication (ATC/DDD; https://www.whocc.no/). HAM-D-17 = Hamilton Depression Rating Scale, 17-items; ACS = Affective Control Scale. BIS = Behavioral Inhibition Scale. BAS-Drive = Behavioral Activation, Drive Subscale; BAS-Reward = Behavioral Activation, Reward Subscale; BAS-Fun Seeking = Behavioral Activation, Fun Seeking Subscale.