Optimization of the bioink. A) Schematic structures of GelMA, alginate,
and PEGOA. B) Schematic depiction of formation of the GAP hydrogel via
crosslinking with CaCl2 and UV exposure. C) Illustration of viscosity
of hydrogels on a slope surface (scale bar, 1 cm). D) Influence of the shear
rate on the rheological behavior of the customized bioink and the different
components of the bioinks. E) G′ and
G″ as a function of time of the bioink and the different
components of the bioink. F) Visual inspection of the customized bioink and the
different components of the bioink after CaCl2 and UV-light exposure.
G) Compressive stress–strain curves for the customized bioink and the
different components of the bioink. H) Young’s modulus of the hydrogels
determined from the stress–strain curves. G: 7% GelMA; A: 2% alginate; P:
2% PEGOA; GA: 7% GelMA and 2% alginate; GP: 7% GelMA and 2% PEGOA; GAP: 7%
GelMA, 2% alginate, and 2% PEGOA.