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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Neurobiol Dis. 2019 Jan 22;125:45–54. doi: 10.1016/j.nbd.2019.01.011

Table 2:

Firing patterns of pallidal burst and tonic neurons (Group1+Group2 = NEW GROUP 1)

GPi
Group 1 (torticollis and laterocollis in the same direction)
GPi
Instantaneous firing rate (sp/s) Coefficient of Variance
Type Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=71) 85 (60-116) 56 (33-85) 0,005 0,87 (0,73-0,91) 0,84 (0,73-0,93) 0,968
Burst (n=162) 69 (47-82) 57 (43-70) 0,026 1,10 (1,01-1,25) 1,13 (1,04-1,25) 0,343
P-value (Tonic vs. burst comparison) 0,009 0,912 <0,001 <0,001
GPe
Instantaneous firing rate (sp/s) Coefficient of Variance
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=64) 58 (36-125) 50 (31-78) p=0,283 0,82 (0,69-0,90) 0,86 (0,72-0,94) p=0,545
Burst (n=89) 51 (36-75) 49 (37-68) p=0,687 1,33 (1,06-1,62) 1,23 (1,10-1,39) p=0,159
P-value (Tonic vs. burst comparison) 0,187 0,840 <0,001 <0,001
Group 2 (torticollis and laterocollis in opposite directions)
Instantaneous firing rate (sp/s) Coefficient of Variance
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=26) 44 (17-79) 80 (18-121) 0,247 0,84 (0,76-0,94) 0,87 (0,84-0,93) 0,662
Burst (n=84) 31 (16-52) 32 (13-57) 0,802 1,25 (1,11-2,04) 1,32 (1,04-2,56) 0,993
P-value (Tonic vs. burst comparison) 0,363 0,006 <0,001 <0,001
GPe
Instantaneous firing rate (sp/s) Coefficient of Variance
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Ipsilateral
Median
(25%-
75%)
Contralateral
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=27) 59 (34-76) 92 (47-124) 0,160 0,78 (0,70-0,87) 0,82 (0,74-0,98) 0,505
Burst (n=51) 68(26-112) 52 (35-78) 0,670 1,08 (0,98-1,31) 1,26 (1,08-1,80) 0,059
P-value (Tonic vs. burst comparison) 0,583 0,162 <0,001 <0,001
Group 3 (retrocollis)
GPi
Instantaneous firing rate (sp/s) Coefficient of Variance
Left
Median
(25%-
75%)
Right
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Left
Median
(25%-
75%)
Right
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=33) 56 (24-80) 36 (19-61) 0,089 0,89 (0,83-0,98) 0,75 (0,61-0,89) 0,018
Burst (n=48) 45 (33-58) 43 (30-56) 0,467 1,23 (1,08-1,39) 1,13 (1,07-1,32) 0,279
P-value (Tonic vs. burst comparison) 0,313 0,403 <0,001 <0,001
GPe
Instantaneous firing rate (sp/s) Coefficient of Variance
Left
Median
(25%-
75%)
Right
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Left
Median
(25%-
75%)
Right
Median
(25%-75%)
P-value
(Ipsilateral
vs
contralateral
comparison)
Tonic (n=23) 74 (58-95) 72 (37-80) 0,497 0,92 (0,85-0,95) 0,86 (0,77-0,94) 0,383
Burst (n=50) 32 (18-48) 42 (26-70) 0,059 1,86 (1,55-2,13) 1,36 (1,10-1,48) 0,003
P-value (Tonic vs. burst comparison) <0,001 0,058 <0,001 <0,001