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. Author manuscript; available in PMC: 2020 Jan 4.
Published in final edited form as: ACS Catal. 2018 Nov 20;9(1):242–252. doi: 10.1021/acscatal.8b04132

Table 2.

Peptide i+3 and N-terminus optimization for directed BV reactiona,b,c

graphic file with name nihms-1007693-t0013.jpg
a

Reaction conditions: Cyclobutanone 4c (0.025 mmol, 1.0 equiv), catalyst (10 mol%), and H2O2 (30% w/w aq. 1.5 equiv) at 0 → 4 °C (ambient temperature) with [4c] = 0.10 M CHCl3.

b

Conversion determined by 1H NMR relative integrations and enantiomeric ratios determined by CSP-HPLC analysis (Chiralpak IA, 230 nm).

c

Reported results are the average of two trials.