Table 2. Comparison between adherent and nonadherent patients with COPD and exertional hypoxemia.a .
| Variable | Patients who adhered to LTOT | Patients who did not adhere to LTOT | p |
|---|---|---|---|
| (n = 18) | (n = 21) | ||
| Men, % | 33.4 | 28.3 | |
| Age, years | 69.1 ± 10.0 | 71.5 ± 8.7 | 0.433 |
| BMI, kg/m2 | 23.2 ± 8.4 | 25.5 ± 6.0 | 0.684 |
| FFM, kg | 45.8 ± 9.3 | 45.0 ± 8.7 | 0.787 |
| FFMI, kg | 17.5 ± 2.1 | 18.1 ± 2.6 | 0.459 |
| Borg scaleb | 0.0 (0.0-1.7) | 0.0 (0.0-0.0) | 0.420 |
| BODE index | 1.1 ± 0.9 | 1.4 ± 1.1 | 0.081 |
| SpO2, % | 93.3 ± 2.3 | 91.1 ± 2.5 | 0.011 |
| PaO2, mmHg | 64.4 ± 6.9 | 62,7 ± 9.1 | 0.536 |
| PaCO2, mmHgb | 35.7 (34.2-39.4) | 39.5 (35.8-47.3) | 0.044 |
| SaO2, %b | 93.3 (90.6-94.3) | 91.2 (90.6-94.1) | 0.509 |
| FVC, Lb | 1.8 (1.4-2.6) | 2.1 (1.5-2.4) | 0.609 |
| FEV1, Lb | 0.9 (0.7-1.0) | 1.0 (0.8-1.3) | 0.083 |
| FEV1/FVC, L | 0.4 ± 0.1 | 0.5 ± 0.1 | 0.072 |
| SGRQ symptoms domain score, % | 27.6 ± 18.7 | 41.5 ± 19.6 | 0.039 |
| SGRQ activity domain score, %b | 60.4 (45.9-70.3) | 72.9 (66.2-79.7) | 0.014 |
| SGRQ impacts domain score, % | 39.5 ± 15.1 | 27.8 ± 18.3 | 0.047 |
| Total SGRQ score, % | 36.4 ± 17.7 | 49.9 ± 11.9 | 0.012 |
| Anxiety, HADS | 3.1 ± 2.6 | 2.4 ± 1.7 | 0.373 |
| Depression, HADSb | 3.5 (1.0-5.0) | 3.0 (0.0-7.0) | 0.981 |
| mMRC scale | 1.9 ± 0.7 | 1.6 ±1.2 | 0.384 |
| BDIb | 5.0 (4.0-5.0) | 6.0 (3.0-8.0) | 0.392 |
| 6MWD, m | 309.6 ± 90.3 | 266.5 ± 97.1 | 0.190 |
BMI: body mass index; FFM: fat-free mass; FFMI: fat-free mass index; BODE: Body mass index, airflow Obstruction, Dyspnea, and Exercise capacity; SGRQ: Saint George’s Respiratory Questionnaire; HADS: Hospital Anxiety and Depression Scale; mMRC: modified Medical Research Council; BDI: Baseline Dyspnea Index; and 6MWD: six-minute walk distance. aValues expressed as mean ± SD, except where otherwise indicated. bValues expressed as median (interquartile range). p < 0.05 (Student’s t-test or Mann-Whitney test).