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. 2019 Apr 10;6(3):e558. doi: 10.1212/NXI.0000000000000558

Figure 3. Markers of T-cell exhaustion and senescence in patient skeletal muscle samples.

Figure 3

mRNA levels of genes related to T-cell exhaustion (A and B) and T-cell senescence (C) from IMNM (n = 12), sIBM (n = 7), and irMyositis (n = 9) samples. Statistical analysis was performed using Kruskal-Wallis one-way analysis of variance with Dunn multiple comparison test. *p < 0.05; **p < 0.01; ***p < 0.001—difference between displayed groups in log fold changes. #p < 0.05; ##p < 0.01; ###p < 0.001—differences between dCT of patient groups and normal control. IMNM = immune-mediated necrotizing myopathy; irMyositis = myositis induced by immune checkpoint inhibitors; sIBM = sporadic inclusion body myositis.