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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Feb 27;198:54–62. doi: 10.1016/j.drugalcdep.2019.01.027

Figure 1:

Figure 1:

Mean (N=8; ±SEM) A,C) body temperature and B,D) activity rates after A,B) inhalation of the PG vehicle or nicotine (NIC; 1, 10, 30 mg/mL) or C,D) subcutaneous injection of saline or 0.8 mg/kg nicotine. Open symbols indicate a significant difference from both the vehicles at a given time-point and the within-treatment baseline, while shaded symbols indicate a significant difference from the baseline, within treatment condition, only. A significant difference from both 1 and 10 mg/mL NIC inhalation conditions is indicated by &. A significant difference from the baseline, collapsed across treatment condition is indicated with #.