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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Feb 27;198:54–62. doi: 10.1016/j.drugalcdep.2019.01.027

Figure 3:

Figure 3:

Mean (N=8; ±SEM) A) temperature and B) locomotor activity after inhalation of vapor from the propylene glycol (PG) vehicle or nicotine (NIC; 30 mg/mL) in four successive 15 minute intervals (indicated with arrows) with either mecamylamine (Mec) or Saline (Sal) i.p. 15 min prior to the first inhalation interval. Open symbols indicate a significant difference from both PG at the same time point and the point time point immediately prior to each inhalation interval within condition. Significant differences from the PG condition (only) are indicated with *. Significant differences between Saline and Mecamylamine pre-treatment within a vapor inhalation condition are indicated with #. Base = baseline (divided into two 15 minute timepoints).