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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Drug Alcohol Depend. 2019 Feb 27;198:54–62. doi: 10.1016/j.drugalcdep.2019.01.027

Figure 4:

Figure 4:

Mean (N=8; ±SEM) A) temperature and B) activity rate after inhalation of vapor from the PG vehicle, nicotine (NIC; 30 mg/mL), Δ9-tetrahydrocannabinol (THC; 25 mg/mL) or the combination for 30 minutes. Mean (N=8; ±SEM) C) temperature and D) activity rate after injection of nicotine (NIC; 0.4 mg/kg, i.p.), Δ9-tetrahydrocannabinol (THC; 5 mg/kg, i.p.) or the combination. Open symbols indicate a significant difference from both vehicle at a given time-point and the within-treatment baseline, while shaded symbols indicate a significant difference from the baseline only. Significant differences from the PG condition (only) are indicated with *. A significant difference from both NIC and THC conditions is indicated by & and from NIC by #.