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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Blood Rev. 2019 Jan 28;35:7–17. doi: 10.1016/j.blre.2019.01.003

Figure 2: Phagocytosis of pRBCs is increased in GTKO-sensitized baboons.

Figure 2:

When GTKO-sensitized baboon serum (gray) was added to human and pig RBCs, there was significantly increased phagocytosis of WT and GTKO pRBCs, but decreased phagocytosis of human AB RBCs. When pooled human O serum (white) was added, human ABO-incompatible (AB) RBCs underwent greater phagocytosis than pRBCs. The small increase in phagocytosis of human group O RBCs likely reflects binding of baboon anti-human antibodies to the RBCs. *P<0.05, **P<0.01. (Modified with permission from reference [52])