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. Author manuscript; available in PMC: 2020 May 1.
Published in final edited form as: Blood Rev. 2019 Jan 28;35:7–17. doi: 10.1016/j.blre.2019.01.003

Figure 4: Flow cytometric comparison of human IgM and IgG antibody binding to pig and human RBCs.

Figure 4:

Human IgM (left) and IgG (right) binding to WT, GTKO, GTKO/βGalNT2-KO (DKO), and GTKO/βGalNT2-KO/CMAHKO (TKO) pig RBCs and to human RBCs. The significant differences in human IgM and IgG binding to the various RBCs are indicated (*p<0.05, **p<0.01; ‡<0.05). There was no IgM/IgG binding to TKO pig or human RBCs (ns = not significant). (A relative Mean Fluorescence Intensity [MFI] <1 indicates no significant binding of IgM or IgG).