Table 3: Carbohydrates known to be expressed on pRBCs against which humans have natural (preformed) antibodies.
Carbohydrate | Enzyme | References |
---|---|---|
Gal (Galactose-α1,3-galactose) |
GT (α1,3-galactosyltransferase) |
Cooper 1992 [54] Good 1992 [55] Phelps 2003 [49] Rouhani 2004 [51] Long 2009 [52] |
Neu5Gc (N-glycolylneuraminic acid) |
CMAH (cytidine monophosphate-N-acetylneuraminic acid hydroxylase) |
Zhu 2002 [59] Padler-Karavani 2011 [60] Burlak 2014 [141] Wang 2014 [142] Lee 2016 [66] |
Sda | β4GalNT2 (β1,4N-acetylgalactosaminyltransferase) |
Byrne 2014 [61] Estrada 2015 [64] Byrne 2018 [62] Zhao 2018 [63] |