. Author manuscript; available in PMC: 2020 Apr 15.

Published in final edited form as: Clin Cancer Res. 2018 Nov 21;25(8):2392–2402. doi: 10.1158/1078-0432.CCR-18-3200

Table 1:

Effect of tsMHC-II in murine models

Tumor Site(s) of Origin	MHC-II induced by transduction of	tsMHC-II associated with	Ref(s)
Breast, sarcoma, lung, colon	IFNG, MHC-II (A^k), Ciita	Tumor rejection and/or inhibited growth	^{18,100,101,106–108}
Breast, lung, colon	Ciita	Resistance to challenge with parental cells	^18,107
Lung	Ciita	Increased tumor growth (only in high MHC-II expressing clones)	¹⁰³
Sarcoma, Lung	MHC-II and Ii or Ciita	No change in tumor growth	^28,103,104
Breast, Lung	IFNG, Ciita	Vaccination with killed tumor cells leads to resistance to re-challenge with parental	^{100,103,107,134,135}
Breast	Ciita	IFN-γ production by splenocytes	¹⁸