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. Author manuscript; available in PMC: 2020 Apr 15.
Published in final edited form as: Cancer Res. 2019 Feb 28;79(8):2054–2064. doi: 10.1158/0008-5472.CAN-18-2732

Figure 2. Raman spectra of radiation-resistant and sensitive tumors.

Figure 2.

(A) Mean Raman spectra (with the shadow representing 1 standard deviation) acquired from lung tumors derived from parental A549 and radiation-resistant (rA549) cells and head and neck tumors derived from radiation-sensitive UM-SCC-22B and radiation-resistant UM-SCC-47 cells. Each of the types were either exposed to fractionated radiation (XT) or sham radiation (NT). (B) A subset of relevant MCR loading vectors derived from the spectra of lung tumors belonging to all the four study classes. The spectra B1 through B4 represent lipid-rich, glycogen-rich, nucleic acid-rich and collagen-rich loadings, respectively. (C) A subset of relevant MCR loading vectors derived from the spectra of tumors belonging to head and neck tumor dataset. The spectra C1 through C3 represent lipid-rich, nucleic acid-rich and collagen-rich loadings, respectively.