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. Author manuscript; available in PMC: 2020 Apr 1.
Published in final edited form as: J Pept Sci. 2019 Feb 27;25(4):e3155. doi: 10.1002/psc.3155

Table 4.

Pharmacokinetic parameters of FITC-AAR029b and its DSPC: Chol:mPEG2000-DSPE liposome formulation after intravenous bolus administration of 0.01 mg/kg FITC (equiv) to Sprague-Dawley rats. AUC, area under the curve; t1/2α, distribution half life, t1/2β, elimination half life; CL, clearance; and VD, volume of distribution. Data were obtained by two repeats of the experiment.

Compound t1/2α
(h)
t1/2β
(h)
AUC 0-inf
(μg h/ml)
CL
(ml/h)
VD
(ml)
FITC-AAR029b 0.029±0.01 2.92±0.93 0.04±0.04 136.41±30.74 541.89±118.56
FITC-AAR029b in Liposome 0.032±0.005 8.87±3.17 0.41±0.003 9.81±0.06 128.14±41.22