Table 2.
Y-BOCS Scores at Baseline and During Five Stimulation Phases
| Patient | Baseline | amSTN | VC/VS | COMB | OPT | AdCBT |
|---|---|---|---|---|---|---|
| 1 | 38 | 32 (16)a | 22 (42) | 17 (55) | 18 (53) | 13 (66) |
| 2 | 34 | 26 (23) | 29 (15) | 23 (32) | 20 (41) | 21 (38) |
| 3 | 37 | 17 (55) | 18 (51) | 12 (68) | 10 (73) | 2 (95) |
| 4 | 38 | 20 (47) | 13 (66) | 16 (58) | 10 (74) | 7 (82) |
| 5 | 34 | 23 (32) | 17 (50) | 17 (50) | 15 (56) | 13 (62) |
| 6 | 36 | 1 (97) | 3 (92) | 0 (100) | 13 (64) | 0 (100) |
| Mean ± SEM | 36.17 ± 0.75 | 19.83 ± 4.32 | 17.00 ± 3.57 | 14.17 ± 3.18 | 14.33 ± 1.69 | 9.33 ± 3.21 |
Values in parentheses indicate % reduction from baseline. amSTN deep brain stimulation was the initial condition for patients 4, 5, and 6.
AdCBT, optimal combined settings plus adjunctive cognitive behavioral therapy; amSTN, anteromedial subthalamic nucleus; COMB, combined phase; OPT, optimal combined settings; VC/VS, ventral capsule/ventral striatum; Y-BOCS, Yale-Brown Obsessive Compulsive Scale.
a
This score is last entry carried forward. Y-BOCS scores range from 1 to 40 and are categorized according to severity as follows: 0–7 = subclinical; 8–15 = mild; 16–23 = moderate; 24–31 = severe; 32–40 = extreme.