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. 2019 Apr 16;9:6161. doi: 10.1038/s41598-019-42450-0

Table 1.

Immunofluorescence analysis of cytoplasmic p27 expression in osteosarcoma tumors.

Score Biopsy (n = 11) Definitive Surgery (n = 29) Metastatic Tumor (n = 15)
p27-Negative 6 (55%) 10 (34%) 2 (14%)
+ 1 (9%) 8 (28%) 3 (20%)
++ 4 (36%) 9 (31%) 5 (33%)
+++ 2 (7%) 5 (33%)

p27 cytoplasmic expression was scored as negative or positive (+/weak, ++/medium, +++/strong).