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. 2019 Apr 16;9:6114. doi: 10.1038/s41598-019-42273-z

Table 3.

Cell cycle analysis in L. (L.) infantum promastigotes treated with compound 2.

Groups Proportion of promastigotes in different stages of cell cycle (% ± SD)
Sub G0 G0/G1 S M/G2
Untreated control 1.3 ± 0.1 67.5 ± 1.9 9.2 ± 0.3 20.9 ± 2.1
2 3.0 ± 0.2** 52.3 ± 1.1** 13.7 ± 0.7** 26.4 ± 0.1*
Miltefosine 10.1 ± 0.2*** 36.4 ± 1.3*** 12.3 ± 0.1* 31.4 ± 0.5**

Sub G0: fragmented DNA, cell death; G0/G1: diploid cells (2N); S: DNA replication; G2/M: cells with duplicated DNA content; SD: Standard deviation. *p < 0.05, **p < 0.01 and ***p < 0.001.