Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 Apr 10;10:735. doi: 10.3389/fimmu.2019.00735

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 Phaahla, Lassaunière, Da Costa Dias, Waja, Martinson and Tiemessen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

NK cell-mediated ADCC responses at different effector-to-target (E:T) cell ratios. NK cells isolated from eight HIV-1 negative donors were tested at different E:T ratios in an HIV-specific GranToxiLux assay using an ADCC-mediating monoclonal antibody (A32) at 2.5 μg/ml. The mean fraction of Granzyme B activity observed at an E:T of 0.5:1 relative to 10:1 was used to calculate a 99% confidence level cut-off value for NK cell-mediated ADCC responses at an E:T of 0.5:1. Data points represent the mean of triplicate measures and the standard deviation indicated by error bars.