Table 1.

PICOS scheme.

PICOS
Patient population	Healthy controls undergoing MRI or echocardiography Aortic coarctation patients undergoing MRI or echocardiography Aortic stenosis patients undergoing MRI or echocardiography
Interventions	Dynamic exercise Dobutamine infusion Isometric exercise
Comparators	Resting state
Outcomes	Primary Heart rate [bpm] Blood flow/stroke volume [ml] Cardiac output [l/min] Additional Systolic ejection time [ms] Time to peak aortic flow rate [ms]
Study design	Interventional studies with or without control group