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. 2019 Apr 10;10:744. doi: 10.3389/fimmu.2019.00744

Figure 3.

Figure 3

Kctd9 is required for NK cells maturation. (A) Flow cytometric analysis for expression of CD11b and CD27 by CD3−DX5+ cells in four organs from WT and Kctd9−/− mice. Numbers in the quadrants indicate the percentage of subsets defined by CD11b/CD27 expression in CD3−DX5+ cells. (B) Summary of the percentages of subsets in CD3−DX5+ cells. (C) The ratio of the CD11b+ subset to the CD11b− subset among CD3−DX5+ cells in indicated organs. (D) The ratio of the CD27− subset to the CD27+ subset among CD3−DX5+CD11b+ cells in indicated organs. (E) The percentages of subsets defined by CD11b/CD27 expression in CD3−NKp46+ NK cells in BM from WT and Kctd9−/− mice. All results were representative of three independent experiments. Four to six mice of each genotype were used in each experiment. Error bars indicate standard deviation. *P < 0.05, **P < 0.01, ***P < 0.001, and ****P < 0.0001.