Table 1.
Phenotype of JO4 derivatives.
| Protein | DSG2 binding | VIA IC50 (µg/mL) |
|---|---|---|
| JO-4 | Yes | 0.067 |
| GB1 | Yes | 0.025 |
| GB2 | Yes | 0.030 |
| GB3 | Yes | 0.029 |
| GB4 | Yes | 0.037 |
| GB5 | Minimal | 0.241 |
| GB6 | n/a | n/a |
| GB7/JOC-x | Yes | 0.032 |
| GB8 | Yes | 0.012 |
| GB9 | No | >10 |
| GB10 | Yes | 0.026 |
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