Table 2.

Biacore analysis of binding to hDSG-2.

Protein	ka (M/s)	Kd (1/s)	KD (nM)
a. Rates following immobilization of hDSG2 protein
JO4	2.32 × 105	2.64 × 10−3	11.4
GB3V239D	4.4 × 10 6	5.0 × 10−4	0.11
GB7V239D/JOC-x	1.4 × 106	8.3 × 10−4	0.58
b. Rates following immobilization of junction opener proteins
JO4	7.9 × 105	4.6 × 10 −4	0.58
GB3V239D	Not tested
GB7V239D/JOC-x	6.3 × 105	7.5 × 10−4	1.19