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. 2019 Apr 16;51(4):43. doi: 10.1038/s12276-019-0241-3

Fig. 3. Development of a novel PDX model of glioblastoma via intravitreal injection.

Fig. 3

a A schematic diagram demonstrating the intravitreal injection of tumor cells. b The relative proportion of mice with grade 2–5 disease after the intravitreal injection of GBL-28 and GBL-37 cells that underwent normal culture conditions. c The relative proportion of mice with grade 3 or 4 disease after the intravitreal injection of GBL-28 and GBL-37 cells that underwent hypoxia treatment for 4 h before injection. d Representative images of H&E-stained sections of the eyeball at 4 weeks after the intravitreal injection of GBL-28 or GBL-37 cells that underwent hypoxia treatment for 4 h before injection. The yellow dashed lines indicate the lens and retina. Scale bar: 1 mm